Illustration | Title | Date of Publication |
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Artificial Internalizing Receptors: Intracellular Delivery of Cargo Through Bio-Orthogonal Recognition Søgaard, A. B., Hansson, R. F., Tvilum, A. S., Zelikin, A. N., Artificial Internalizing Receptors: Intracellular Delivery of Cargo Through Bio-Orthogonal Recognition. Adv. Healthcare Mater. 2024, 2402472. | 2024-10-21 | |
Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis Søgaard, A. B., Løvschall, K. B., Montasell, M. C., Cramer C. B., Marcet, P. M., Pedersen, A. B., Jakobsen, J. H., Zelikin, A. N., Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis. Adv. Biology 2024, 2400053. | 2024-05-20 | |
Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells Søgaard, A. B., Skovbo, F., Tvilum, A., Hansson, R. F., Zelikin, A. N., Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells. Adv. Funct. Mater. 2024, 2400048. | 2024-04-01 | |
Zymogens and Transmembrane Activation of Transcription in Synthetic Cells Andersen, D. G., Pedersen, A. B., Jørgensen, M. H., Montasell, M. C., Søgaard, A. B., Chen, G., Schroeder, A., Andersen, G. R., Zelikin, A. N., Zymogens and Transmembrane Activation of Transcription in Synthetic Cells. Adv. Mater. 2024, 2309385. | 2023-11-27 | |
Mechanisms of Degradation for Polydisulfides: Main Chain Scission, Self-Immolation, Or Chain Transfer Depolymerization Kristensen, M. M.; Løvschall, K. B.; Zelikin, A. N. Mechanisms of Degradation for Polydisulfides: Main Chain Scission, Self-Immolation, Or Chain Transfer Depolymerization. ACS Macro Lett. 2023, 955-960. | 2023-06-29 | |
Antibody-Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release Tvilum, A., Johansen, M. I., Glud, L. N. et al. Antibody-Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release. Adv. Sci. 2023, 2301340 | 2023-06-08 | |
Chemical zymogens: specificity and steroidal control of reactivation Montasell, Mireia Casanovas, Baumann, Anna, Zelikin, Alexander N. ChemBioChem (2023) | 2023-04-18 | |
Transmembrane signaling by a synthetic receptor in artificial cells Søgaard, A.B., Pedersen, A.B., Løvschall, K.B. et al. Transmembrane signaling by a synthetic receptor in artificial cells. Nat Commun 14, 1646 (2023) | 2023-03-24 | |
Potentiation of Drug Toxicity through Virus Latency Reversal Promotes Preferential Elimination of HIV Infected Cells Truong, T. T., Hayn, M., Frich, C. K., Olari, L.-R., Ladefoged, L. K., Olesen, M. T. J., Jakobsen, J. H., Lunabjerg-Vestergaard, C. K., Schiøtt, B., Münch, J., Zelikin, A. N. Adv. Therap. 2022, 2200113. | 2022-08-22 | |
Chemical zymogens for the protein cysteinome Montasell, M.C., Monge, P., Carmali, S. et al. Nat Commun 2022, 13, 4861 | 2022-08-18 | |
Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability Harms M, Hansson RF, Carmali S, et al. Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability. Bioconjug. Chem. 2022, 33, 594-607. | 2022-03-16 | |
Ceria Nanozyme and Phosphate Prodrugs: Drug Synthesis through Enzyme Mimicry Raoul Walther, Tin H. Huynh, Pere Monge, Anne Sofie Fruergaard, Aref Mamakhel, and Alexander N. Zelikin ACS Appl. Mater. Interfaces 2021, 13, 22, 25685–25693 | 2021-05-25 | |
Per-glycosylation of the Surface-Accessible Lysines: One-Pot Aqueous Route to Stabilized Proteins with Native Activity R. Walther, P. Monge, A. B. Pedersen, A. Benderoth, J. N. Pedersen, A. Farzadfard, O. A. Mandrup, K. A. Howard, D. E. Otzen, A. N. Zelikin, ChemBioChem 2021, 22, 2478. | 2021-05-16 | |
Synthetic Artificial Apoptosis-Inducing Receptor for On-Demand Deactivation of Engineered Cells Monge, P., Løvschall, K. B., Søgaard, A. B., Walther, R., Golbek, T. W., Schmüser, L., Weidner, T., Zelikin, A. N., Synthetic Artificial Apoptosis-Inducing Receptor for On-Demand Deactivation of Engineered Cells. Adv. Sci. 2021, 8, 2004432 | 2021-05-01 | |
Chemical (neo)glycosylation of biological drugs Walther, R; Zelikin, A.N. Adv. Drug Deliv. Rev 2021, 171, 62-76 | 2021-04 | |
Synthetic chemical ligands and cognate antibodies for biorthogonal drug targeting and cell engineering P. Monge, A. B. Søgaard, D. G. Andersen, R. Chandrawati, A. N. Zelikin Adv. Drug Deliv. Rev 2021, 170, 281-293 | 2021-03 | |
Inhaled and systemic heparin as a repurposed direct antiviral drug for prevention and treatment of COVID-19 Conzelmann, C.; Müller, J.A.; Perkhofer, L.; Sparrer, K.; Zelikin, A.N.; Münch, J.; Kleger, A. Clin. Med. 2020, 20 (6), e218-221 | 2020-11 | |
Nanozymes and Glucuronides: Glucuronidase, Esterase, and/or Transferase Activity Walther, R.; van den Akker, W.; Fruergaard, A.S.; Zelikin, A.N.* Small 2020, 16 (44), 2004280 | 2020-10-13 | |
Chemical Artificial Internalizing Receptors for Primary T cells P. Monge, A. Tvilum, A. B. Søgaard, K. Borup Løvschal, M. T. Jarlstad Olesen, A.N Zelikin Adv. Sci 2020, 7, 20013951907635 | 2020-07-26 | |
Remotely Triggered Liquefaction of Hydrogel Materials Søren L. Pedersen, Tin H. Huynh, Philipp Pöschko, Anne Sofie Fruergaard, Morten T. Jarlstad Olesen, Yaqing Chen, Henrik Birkedal, Guruprakash Subbiahdoss, Erik Reimhult, Jan Thøgersen, and Alexander N. Zelikin ACS Nano 2020, 14, 7, 9145–9155 | 2020-07-02 | |
Enzyme Mimics for the Catalytic Generation of Nitric Oxide from Endogenous Prodrugs from Endogenous Prodrugs Yang, T., Zelikin, A. N., Chandrawati, R. Small 2020, 1907635 | 2020-05-05 | |
S-nitrosothiol-terminated poly(vinyl alcohol): Nitric oxide release and skin blood flow response Leonardo P. Giglio, Guilherme F. Picheth, Kaja Borup Løvschall, Alexander N. Zelikin, Marcelo G. de Oliveira Ntiric Oxide 2020, 98, 41-49 | 2020-05-01 | |
Molecular, Macromolecular, and Supramolecular Glucuronide Prodrugs: Lead Identified for Anticancer Prodrug Monotherapy M. T. Jarlstad Olesen, R. Walther, P. P. Poier, F. Dagnæs-Hansen, A. N. Zelikin Angew. Chem. Int. Ed. 2020 , 59 , 7390 | 2020-02-19 | |
Zinc Oxide Particles Catalytically Generate Nitric Oxide from Endogenous and Exogenous Prodrugs Yang, T., Fruergaard, A. S., Winther, A. K., Zelikin, A. N., Chandrawati, R. Small 2020, 1906744. | 2020-03-05 | |
Extended scaffold glucuronides: en route to the universal synthesis of O-aryl glucuronide prodrugs R. Walther, M. T. Jarlstad Olesen, A.N. Zelikin Org. Biomol. Chem., 2019,17, 6970-6974 | 2019-07-10 |