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Publications

IllustrationTitleDate of Publication
Artificial Internalizing Receptors: Intracellular Delivery of Cargo Through Bio-Orthogonal Recognition
Søgaard, A. B., Hansson, R. F., Tvilum, A. S., Zelikin, A. N., Artificial Internalizing Receptors: Intracellular Delivery of Cargo Through Bio-Orthogonal Recognition. Adv. Healthcare Mater. 2024, 2402472.
2024-10-21
Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis
Søgaard, A. B., Løvschall, K. B., Montasell, M. C., Cramer C. B., Marcet, P. M., Pedersen, A. B., Jakobsen, J. H., Zelikin, A. N., Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis. Adv. Biology 2024, 2400053.
2024-05-20
Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells
Søgaard, A. B., Skovbo, F., Tvilum, A., Hansson, R. F., Zelikin, A. N., Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells. Adv. Funct. Mater. 2024, 2400048.
2024-04-01
Zymogens and Transmembrane Activation of Transcription in Synthetic Cells
Andersen, D. G., Pedersen, A. B., Jørgensen, M. H., Montasell, M. C., Søgaard, A. B., Chen, G., Schroeder, A., Andersen, G. R., Zelikin, A. N., Zymogens and Transmembrane Activation of Transcription in Synthetic Cells. Adv. Mater. 2024, 2309385.
2023-11-27
Mechanisms of Degradation for Polydisulfides: Main Chain Scission, Self-Immolation, Or Chain Transfer Depolymerization
Kristensen, M. M.; Løvschall, K. B.; Zelikin, A. N. Mechanisms of Degradation for Polydisulfides: Main Chain Scission, Self-Immolation, Or Chain Transfer Depolymerization. ACS Macro Lett. 2023, 955-960.
2023-06-29
Antibody-Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release
Tvilum, A., Johansen, M. I., Glud, L. N. et al. Antibody-Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release. Adv. Sci. 2023, 2301340
2023-06-08
Chemical zymogens: specificity and steroidal control of reactivation
Montasell, Mireia Casanovas, Baumann, Anna, Zelikin, Alexander N.
ChemBioChem (2023)
2023-04-18
Transmembrane signaling by a synthetic receptor in artificial cells
Søgaard, A.B., Pedersen, A.B., Løvschall, K.B. et al. Transmembrane signaling by a synthetic receptor in artificial cells. Nat Commun 14, 1646 (2023)
2023-03-24
Potentiation of Drug Toxicity through Virus Latency Reversal Promotes Preferential Elimination of HIV Infected Cells
Truong, T. T., Hayn, M., Frich, C. K., Olari, L.-R., Ladefoged, L. K., Olesen, M. T. J., Jakobsen, J. H., Lunabjerg-Vestergaard, C. K., Schiøtt, B., Münch, J., Zelikin, A. N. Adv. Therap. 2022, 2200113.
2022-08-22
Chemical zymogens for the protein cysteinome
Montasell, M.C., Monge, P., Carmali, S. et al. Nat Commun 2022, 13, 4861
2022-08-18
Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability
Harms M, Hansson RF, Carmali S, et al. Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability. Bioconjug. Chem. 2022, 33, 594-607.
2022-03-16
Ceria Nanozyme and Phosphate Prodrugs: Drug Synthesis through Enzyme Mimicry
Raoul Walther, Tin H. Huynh, Pere Monge, Anne Sofie Fruergaard, Aref Mamakhel, and Alexander N. Zelikin
ACS Appl. Mater. Interfaces 2021, 13, 22, 25685–25693
2021-05-25
Per-glycosylation of the Surface-Accessible Lysines: One-Pot Aqueous Route to Stabilized Proteins with Native Activity
R. Walther, P. Monge, A. B. Pedersen, A. Benderoth, J. N. Pedersen, A. Farzadfard, O. A. Mandrup, K. A. Howard, D. E. Otzen, A. N. Zelikin, ChemBioChem 2021, 22, 2478.
2021-05-16
Synthetic Artificial Apoptosis-Inducing Receptor for On-Demand Deactivation of Engineered Cells
Monge, P., Løvschall, K. B., Søgaard, A. B., Walther, R., Golbek, T. W., Schmüser, L., Weidner, T., Zelikin, A. N., Synthetic Artificial Apoptosis-Inducing Receptor for On-Demand Deactivation of Engineered Cells. Adv. Sci. 2021, 8, 2004432
2021-05-01
Chemical (neo)glycosylation of biological drugs
Walther, R; Zelikin, A.N.
Adv. Drug Deliv. Rev 2021, 171, 62-76
2021-04
Synthetic chemical ligands and cognate antibodies for biorthogonal drug targeting and cell engineering
P. Monge, A. B. Søgaard, D. G. Andersen, R. Chandrawati, A. N. Zelikin
Adv. Drug Deliv. Rev 2021, 170, 281-293
2021-03
Inhaled and systemic heparin as a repurposed direct antiviral drug for prevention and treatment of COVID-19
Conzelmann, C.; Müller, J.A.; Perkhofer, L.; Sparrer, K.; Zelikin, A.N.; Münch, J.; Kleger, A.
Clin. Med. 2020, 20 (6), e218-221
2020-11
Nanozymes and Glucuronides: Glucuronidase, Esterase, and/or Transferase Activity
Walther, R.; van den Akker, W.; Fruergaard, A.S.; Zelikin, A.N.*
Small 2020, 16 (44), 2004280
2020-10-13
Chemical Artificial Internalizing Receptors for Primary T cells
P. Monge, A. Tvilum, A. B. Søgaard, K. Borup Løvschal, M. T. Jarlstad Olesen, A.N Zelikin
Adv. Sci 2020, 7, 20013951907635
2020-07-26
Remotely Triggered Liquefaction of Hydrogel Materials
Søren L. Pedersen, Tin H. Huynh, Philipp Pöschko, Anne Sofie Fruergaard, Morten T. Jarlstad Olesen, Yaqing Chen, Henrik Birkedal, Guruprakash Subbiahdoss, Erik Reimhult, Jan Thøgersen, and Alexander N. Zelikin
ACS Nano 2020, 14, 7, 9145–9155
2020-07-02
TOC_NOxnanozymes_small3@4xEnzyme Mimics for the Catalytic Generation of Nitric Oxide from Endogenous Prodrugs from Endogenous Prodrugs
Yang, T., Zelikin, A. N., Chandrawati, R.
Small 2020, 1907635
2020-05-05
TOC_Leo_Small@4xS-nitrosothiol-terminated poly(vinyl alcohol): Nitric oxide release and skin blood flow response
Leonardo P. Giglio, Guilherme F. Picheth, Kaja Borup Løvschall, Alexander N. Zelikin, Marcelo G. de Oliveira
Ntiric Oxide 2020, 98, 41-49
2020-05-01
TOC_glucuronides_small@4xMolecular, Macromolecular, and Supramolecular Glucuronide Prodrugs: Lead Identified for Anticancer Prodrug Monotherapy
M. T. Jarlstad Olesen, R. Walther, P. P. Poier, F. Dagnæs-Hansen, A. N. Zelikin
Angew. Chem. Int. Ed. 2020 , 59 , 7390
2020-02-19
TOC_ZnO_Small_Small@4xZinc Oxide Particles Catalytically Generate Nitric Oxide from Endogenous and Exogenous Prodrugs
Yang, T., Fruergaard, A. S., Winther, A. K., Zelikin, A. N., Chandrawati, R.
Small 2020, 1906744.
2020-03-05
TOC_extended_scaffold@4xExtended scaffold glucuronides: en route to the universal synthesis of O-aryl glucuronide prodrugs
R. Walther, M. T. Jarlstad Olesen, A.N. Zelikin
Org. Biomol. Chem., 2019,17, 6970-6974
2019-07-10

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